PRAK Products

Description

PRAK is encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.

Bioinformatics

Entrez	8550 Human
Uniprot	AAH47284 Human NP_003659 Human NP_003659.2 Human NP_620777 Human Q8IW41 Human
Product By Gene ID	8550
Alternate Names	EC 2.7.11 MAP kinase-activated protein kinase 5 MAPK-activated protein kinase 5 MAPKAP kinase 5 MAPKAPK-5 mitogen-activated protein kinase-activated protein kinase 5 p38-regulated/activated protein kinase PRAKEC 2.7.11.1

Research Areas for PRAK

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Phospho-Specific
Protein Kinase