PP2A alpha [p Tyr307] Antibody (4B10)

Product Discontinued

PP2A alpha [p Tyr307] Antibody (4B10) Summary

• Immunogen: Peptide corresponding to residues 302-309 of human PP2A; recognizes phosphorylated PP2A on tyrosine 307.
• Modification: p Tyr307
• Specificity: PP2A phosphorylated on tyrosine 307.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PPP2CA
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA 1:2000-1:5000
• Application Notes: Not recommended for WB.
• Theoretical MW: 36 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Vertebrates

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: Mouse ascites with 30% Glycerol
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Notes

Relevant Entrez Gene Numbers: NM_004156

Alternate Names for PP2A alpha [p Tyr307] Antibody (4B10)

• EC 3.1.3.16
• PP2A
• PP2A-alpha
• PP2Ac
• PP2CA
• PP2Calpha
• PPP2CA
• protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform
• protein phosphatase 2, catalytic subunit, alpha isozyme
• protein phosphatase 2A catalytic subunit, alpha isoform
• Replication protein C
• RP-C
• serine/threonine protein phosphatase 2A, catalytic subunit, alpha isoform
• serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

Background

Protein phosphatase type 2A (PP2A ) is a protein serine/threonine phosphatase that controls fundamental cellular processes, including transcription, translation, metabolism, cell growth, apoptosis, and varied other signal transduction pathways. PP2A is comprised of a core enzyme (which is made up of catalytic C and regulatory A (PR65) subunits) and a secondary regulatory B subunit. PP2A alpha refers to the alpha isoform of the PP2A catalytic subunit.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPP2CA
• Uniprot:
  • P67775()