Polycystin 2 Antibody (4C8)

Images

 
Western Blot: Polycystin 2 Antibody (4C8) [H00005311-M01] - PKD2 monoclonal antibody (M01), clone 4C8. Analysis of PKD2 expression in human liver.
Immunocytochemistry/ Immunofluorescence: Polycystin 2 Antibody (4C8) [H00005311-M01] - Analysis of monoclonal antibody to PKD2 on HeLa cell. Antibody concentration 10 ug/ml.
Sandwich ELISA: Polycystin 2 Antibody (4C8) [H00005311-M01] - Detection limit for recombinant GST tagged PKD2 is approximately 0.3ng/ml as a capture antibody.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, ICC/IF
Clone
4C8
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Polycystin 2 Antibody (4C8) Summary

Immunogen
PKD2 (NP_000288 261 a.a. - 360 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. PVSKTEKTNFKTLSSMEDFWKFTEGSLLDGLYWKMQPSNQTEADNRSFIFYENLLLGVPRIRQLRVRNGSCSIPQDLRDEIKECYDVYSVSSEDRAPFGP
Specificity
PKD2 - polycystic kidney disease 2 (autosomal dominant)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PKD2
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Polycystin 2 Antibody (4C8)

  • APKD2
  • Autosomal dominant polycystic kidney disease type II protein
  • MGC138466
  • MGC138468
  • PC2
  • Pc-2
  • PKD4
  • polycystic kidney disease 2 (autosomal dominant)
  • Polycystic kidney disease 2 protein
  • polycystin-2
  • polycystwin
  • R48321
  • transient receptor potential cation channel, subfamily P, member 2
  • TRPP2

Background

This gene encodes a member of the polycystin protein family. The encoded protein contains multiple transmembrane domains, and cytoplasmic N- and C-termini. The protein may be an integral membrane protein involved in cell-cell/matrix interactions. The encoded protein may function in renal tubular development, morphology, and function, and may modulate intracellular calcium homoeostasis and other signal transduction pathways. This protein interacts with polycystin 1 to produce cation-permeable currents. Mutations in this gene have been associated with autosomal dominant polycystic kidney disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PKD2
Entrez
OMIM
Uniprot