PLA2G1B Antibody (630823) [Alexa Fluor® 750]

• Reactivity: Hu
• Applications: WB, IP
• Clone: 630823
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

PLA2G1B Antibody (630823) [Alexa Fluor® 750] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human PLA2G1B
  Met1-Ser148
  Accession # NM_000928
• Specificity: Detects human PLA2G1B in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) PLA2G2A, rhPLA2G7, recombinant mouse (rm) PLA2G2A, or rmPLA2R1 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PLA2G1B Antibody (630823) [Alexa Fluor® 750]

• Group IB phospholipase A2
• Phosphatidylcholine 2-acylhydrolase 1B
• phospholipase A2
• phospholipase A2, group IB (pancreas)
• PLA2
• PLA2A
• PLA2AMGC119834
• PLA2EC 3.1.1.4
• PLA2G1B
• PPLA2
• PPLA2MGC119835

Background

PLA2G1B, also called Secretory Phopholipase A2, hydrolyses the sn-2 ester bond of phospholipids, including those in cell membranes, to generate non-esterified free fatty acids and lysophospholipids. Most secretory PLA2s are stored in cytoplasmic granules and are released into plasma and biological fluids on appropriate cell activation, especially during systemic inflammatory, autoimmune, or allergic disease. PLA2G1B is abundant in digestive organs but is also found elsewhere. Human PLA2G1B shares 78% and 76% amino acid sequence identity with mouse and rat PLA2G1B, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.