PAC2 Antibody (OTI1E8) [HRP]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI1E8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

PAC2 Antibody (OTI1E8) [HRP] Summary

• Immunogen: Full length recombinant protein of human PAC2 (NP_064617) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PSMG2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for PAC2 Antibody (OTI1E8) [HRP]

• CLAST3HSPC260
• HCCA3PAC-2
• hepatocellular carcinoma susceptibility protein
• Hepatocellular carcinoma-susceptibility protein 3
• HsT1707
• likely ortholog of mouse CD40 ligand-activated specific transcript 3 (Clast3)
• MDS003
• MGC15092
• PAC2HDCMC29P
• proteasome (prosome, macropain) assembly chaperone 2
• proteasome assembling chaperone 2
• proteasome assembly chaperone 2
• TNFSF5IP1CD40 ligand-activated specific transcript 3
• Tumor necrosis factor superfamily member 5-induced protein 1
• tumor necrosis factor superfamily, member 5-induced protein 1
• x 003 protein

Background

Chaperone protein which promotes assembly of the 20S proteasome as part of a heterodimer with PSMG1. The PSMG1-PSMG2 heterodimer binds to the PSMA5 and PSMA7 proteasome subunits, promotes assembly of the proteasome alpha subunits into the heteroheptameric alpha ring and prevents alpha ring dimerization

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSMG2