p70 S6 Kinase beta/S6K2 Antibody

Western Blot: p70 S6 Kinase beta/S6K2 Antibody [H00006199-B02P] - Analysis of RPS6KB2 expression in transfected 293T cell line by RPS6KB2 polyclonal antibody. Lane 1: RPS6KB2 transfected lysate(53.02 KDa). Lane 2: Non-transfected lysate.

Immunocytochemistry/Immunofluorescence: p70 S6 Kinase beta/S6K2 Antibody [H00006199-B02P] - Analysis of purified antibody to RPS6KB2 on HeLa cell. (antibody concentration 10 ug/ml)

Product Discontinued

p70 S6 Kinase beta/S6K2 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: RPS6KB2 (AAH06106.3, 1 a.a. - 482 a.a.) full-length human protein. MAAVFDLDLETEEGSEGEGEPELSPADACPLAELRAAGLEPVGHYEEVELTETSVNVGPERIGPHSFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDTRFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRAPVSPLKFSPFEGFRPSPSLPEPTELPLPPLLPPPPPSTTAPLPIRPPSGTKKSKRGRGRPGR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: RPS6KB2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Proximity Ligation Assay
  • Western Blot
• Application Notes: It has been used for WB and Functional.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for p70 S6 Kinase beta/S6K2 Antibody

• EC 2.7.11
• EC 2.7.11.1
• KLS
• p70 ribosomal S6 kinase beta
• p70 S6 Kinase beta
• p70 S6KB
• p70 S6K-beta
• p70(S6K)-beta
• p70-beta
• P70-beta-1
• P70-beta-2
• p70-S6K 2
• P70S6K2
• p70S6Kb
• ribosomal protein S6 kinase beta-2
• ribosomal protein S6 kinase, 70kD, polypeptide 2,70 kDa ribosomal protein S6 kinase 2
• ribosomal protein S6 kinase, 70kDa, polypeptide 2
• RPS6KB2
• S6K2
• S6K-beta
• S6K-beta2
• S6K-beta-2
• serine/threonine-protein kinase 14 beta
• Serine/threonine-protein kinase 14B
• SRK
• STK14B
• STK14BS6 kinase-related kinase

Background

S6K2 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for p70 S6 Kinase beta/S6K2 Antibody (H00006199-B02P)(1)

Publication using H00006199-B02P

• Warner MJ, Bridge KS, Hewitson JP et al. S6K2-mediated regulation of TRBP as a determinant of miRNA expression in human primary lymphatic endothelial cells. Nucleic Acids Res 2016-07-12 [PMID: 27407113]

Bioinformatics

• Gene Symbol: RPS6KB2
• Uniprot:
  • AAH06106.3(Human)