P2Y4/P2RY4 Antibody - BSA Free

Immunohistochemistry-Paraffin: P2Y4/P2RY4 Antibody [NBP3-14439] - Immunohistochemistry of formalin-fixed, paraffin-embedded human pancreas after heat-induced antigen retrieval.

• Reactivity: Hu, Pm, Pm
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

P2Y4/P2RY4 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 16 amino acid peptide from internal region of human P2Y4/P2RY4.
• Epitope: Internal
• Specificity: Human P2Y4/P2RY4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Monkey (94%), Primate (100%). Backed by our 100% Guarantee.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: P2RY4
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Immunohistochemistry: The unconjugated form was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after proteinase K antigen retrieval. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for the unconjugated form was determined to be 10 ug/ml..

Reactivity Notes

Expected reactivity based on percent sequence identity: Bovine, Opossum (88%), Mouse, Rat, Bat, Porcine (81%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for P2Y4/P2RY4 Antibody - BSA Free

• NRU
• P2P
• P2RY4
• P2Y4
• P2Y4P2Y purinoceptor 4
• pyrimidinergic receptor P2Y, G-protein coupled, 4
• UNRNRUUridine nucleotide receptor

Background

The pyrimidinergic receptor P2Y4 (P2RY4) is a member of the Purinergic Receptor subfamily. Membrane-bound P2 receptors mediate the actions of extracellular nucleotides in cell-to-cell signaling. P2Y4 expression has been documented in blood, bone, heart, lung, pancreas, placenta, and umbilical cord.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: P2RY4