P2Y14/GPR105 Antibody - BSA Free

Immunohistochemistry-Paraffin: P2Y14/GPR105 Antibody [NBP3-14438] - Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, neurons and glia, after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: P2Y14/GPR105 Antibody [NBP3-14438] - Immunohistochemistry of formalin-fixed, paraffin-embedded human brain, glioblastoma, after heat-induced antigen retrieval.

Immunohistochemistry: P2Y14/GPR105 Antibody [NBP3-14438] - Immunohistochemistry of lung, non-small cell carcinoma,

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

P2Y14/GPR105 Antibody - BSA Free Summary

• Description: Product can be stored undiluted at 4C for up to 1 month.
• Immunogen: Synthetic 17 amino acid peptide from 2nd extracellular domain of human P2RY14.
• Epitope: Extracellular Domain
• Specificity: Human P2Y14/GPR105. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: P2RY14
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: .

Reactivity Notes

Expected reactivity based on percent sequence identity: Marmoset (88%)

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for P2Y14/GPR105 Antibody - BSA Free

• G protein coupled receptor for UDP-glucose
• GPR105
• G-protein coupled receptor 105
• KIAA0001G protein-coupled receptor 105
• P2RY14
• P2Y purinoceptor 14
• P2Y(14) receptor
• P2Y14 receptor
• P2Y14
• purinergic receptor P2Y, G-protein coupled, 14
• UDP-glucose receptor

Background

GPR105 is a Sugar-Sensing Receptor. GPR105 is a G-protein-coupled receptor identifying a quiescent, primitive population of hematopoietic cells restricted to bone marrow. GPC105 has been suggested to mediates primitive cell responses to specific hematopoietic microenvironments and extends the known immune system functions of P2Y receptors to the stem cell level. GPR105 has also been suggested to play an important role in peripheral and neuroimmune function in response to extracellular UDP-sugars. GPR105 has been reported to be expressed in brain. ESTs have been isolated from kidney, placenta, uterus, and heart/melanocyte/uterus libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: P2RY14