p15INK4b/CDKN2B Antibody (DCS114.1)

Product Discontinued

p15INK4b/CDKN2B Antibody (DCS114.1) Summary

• Immunogen: Mice were immunized with a his-tagged recombinant full length p15 protein recognizing a 15 kDa protein
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: CDKN2B
• Purity: Ammonium sulfate precipitation

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1 - 5 ug/mL
• Application Notes: Immunoprecipitation (co-precipitates cdk4/cdk6)..

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Ammonium sulfate precipitation

Alternate Names for p15INK4b/CDKN2B Antibody (DCS114.1)

• CDK4I
• CDKN2B
• cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
• cyclin-dependent kinases 4 and 6 binding protein
• INK4BCDK4B inhibitor
• MTS2
• MTS-2
• MTS2CDK inhibitory protein
• Multiple tumor suppressor 2
• p14_CDK inhibitor
• p14_INK4B
• p14-INK4b
• p15 CDK inhibitor
• p15_INK4B
• P15cyclin-dependent kinase 4 inhibitor B
• p15INK4b
• p15-INK4b
• TP15

Background

The immunogen for the anti-human p15 was a his-tagged recombinant full length p15 protein recognizing a 15kDa protein. The p15ink4b tumor suppressor protein shows no cross reactivity with the closely related inhibitors including p16ink4a and p19ink4d. p15ink4b is a specific inhibitor of cdk4/cdk6, and is periodically expressed during cell cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDKN2B