p15INK4b/CDKN2B Products

Antibodies
p15INK4b/CDKN2B Antibody
p15INK4b/CDKN2B Antibody
NB100-91906
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
p15INK4b/CDKN2B Antibody
p15INK4b/CDKN2B Antibody
NBP1-67653
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
p15INK4b/CDKN2B Antibody (651 ...
p15INK4b/CDKN2B Antibody (651308) ...
MAB6798
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
Lysates
p15INK4b/CDKN2B Overexpressio ...
p15INK4b/CDKN2B Overexpression Lys...
NBP2-05789
Applications: WB
p15INK4b/CDKN2B Overexpressio ...
p15INK4b/CDKN2B Overexpression Lys...
NBP2-10514
Applications: WB
p15INK4b/CDKN2B Overexpressio ...
p15INK4b/CDKN2B Overexpression Lys...
H00001030-T01
Applications: WB
Proteins
p15INK4b/CDKN2B Recombinant P ...
p15INK4b/CDKN2B Recombinant Protein
H00001030-P01
Species: Hu
Applications: WB, ELISA, PA
p15INK4b/CDKN2B Recombinant P ...
p15INK4b/CDKN2B Recombinant Protei...
NBP2-38023PEP
Species: Hu
Applications: AC
RNAi
p15INK4b/CDKN2B RNAi
p15INK4b/CDKN2B RNAi
H00001030-R02
Species: Hu
p15INK4b/CDKN2B RNAi
p15INK4b/CDKN2B RNAi
H00001030-R01
Species: Hu

Description

The normal progression of cells through the cell cycle is under the control of the cyclin dependent protein kinases Cdk4 and Cdk6 which are subject to inhibition by the mitotic inhibitory protein, p16. An isolated member of the p16 family has been designated p15. p15 expression is upregulated approximately 30-fold in TGFbeta-treated human keratinocytes, suggesting that p15 may act as an effector of TGFbeta-mediated cell cycle arrest. The gene encoding p15 has been mapped to chromosome 9p21 at a position adjacent to the p16 gene at a site of frequent chromosomal abnormality in human tumors. It has been suggested that p15 may function as an effector of TGFbeta-mediated cell cycle arrest through inhibition of Cdk4 and Cdk6 kinases.

Bioinformatics

Uniprot Human
Human
Human
Human
Product By Gene ID 1030
Alternate Names
  • p15INK4B
  • p14-INK4b
  • p15_INK4B
  • MTS-2
  • p15 CDK inhibitor
  • Multiple tumor suppressor 2
  • p14_CDK inhibitor
  • p15INK4b
  • p14_INK4B
  • TP15
  • cyclin-dependent kinases 4 and 6 binding protein
  • CDK4I
  • P15cyclin-dependent kinase 4 inhibitor B
  • INK4BCDK4B inhibitor
  • MTS2CDK inhibitory protein
  • p15-INK4b
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

Research Areas for p15INK4b/CDKN2B

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication

PTMs for p15INK4b/CDKN2B

Learn more about PTMs related to p15INK4b/CDKN2B.

Methylation
Phosphorylation
Demethylation
Reduction
Cleavage
Acetylation

Bioinformatics Tool for p15INK4b/CDKN2B

Discover related pathways, diseases and genes to p15INK4b/CDKN2B. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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