Opsin 3 Antibody

Product Discontinued

Opsin 3 Antibody Summary

• Immunogen: A synthetic peptide as a part of human opsin-3 (OPN3, ECPN, encephalopsin, panopsin) conjugated to immunogenic carrier protein was used as the immunogen.
• Localization: Membrane; Multi-pass membrane protein.
• Specificity: opsin-3.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: OPN3
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Whole antisera
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Unpurified
• Reconstitution Instructions: Please contact technical support for detailed reconstituion instruction.

Notes

Reconstitute in 0.1 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability.

Alternate Names for Opsin 3 Antibody

• ECPN
• ECPNopsin-3
• encephalopsin
• ERO
• NMO-1
• opsin 3 (encephalopsin, panopsin)
• opsin 3
• Panopsin

Background

Opsins are members of the guanine nucleotide-binding protein (G protein)-coupled receptor superfamily. In addition to the visual opsins, mammals possess several photoreceptive non-visual opsins that are expressed in extraocular tissues. This gene, opsin 3, is strongly expressed in brain and testis and weakly expressed in liver, placenta, heart, lung, skeletal muscle, kidney, and pancreas. The gene may also be expressed in the retina. The protein has the canonical features of a photoreceptive opsin protein. FUNCTION: May play a role in encephalic photoreception. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: OPN3
• Entrez:
  • 23596(Human)
• OMIM:
  • OPN3_HUMAN(Human)
• Uniprot:
  • Q9H1Y3(Human)