Olig3 Antibody (257934) [Unconjugated]

• Reactivity: Hu, Mu
• Applications: WB
• Clone: 257934
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: LYOPH

Olig3 Antibody (257934) [Unconjugated] Summary

• Immunogen: E. coli-derived recombinant human Olig3
  Met1-Lys272
  Accession # Q7RTU3
• Specificity: Detects human and mouse Olig3 in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) Olig1 or rhOlig2 is observed.
• Source: N/A
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: OLIG3
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Olig3 Antibody (257934) [Unconjugated]

• BHLHB7
• BHLHE20
• bHLHe20oligo3
• Class B basic helix-loop-helix protein 7
• Class E basic helix-loop-helix protein 20
• Olig3
• Oligo3
• oligodendrocyte transcription factor 3

Background

Olig3 belongs to the Olig family of basic-helix-loop-helix (bHLH) transcription factors. It is transiently expressed in different types of embryonic central nervous system progenitors but is absent in later stages of development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Olig3 Antibody (MAB2456)(4)

Publications using MAB2456

• B Sanders, D D'Andrea, MO Collins, E Rees, TGJ Steward, Y Zhu, G Chapman, SE Legge, AF Pardiñas, AJ Harwood, WP Gray, MC O'Donovan, MJ Owen, AC Errington, DJ Blake, DJ Whitcomb, AJ Pocklingto, E Shin Transcriptional programs regulating neuronal differentiation are disrupted in DLG2 knockout human embryonic stem cells and enriched for schizophrenia and related disorders risk variants Nature Communications, 2022-01-14;13(1):27. 2022-01-14 [PMID: 35031607] (ICC, Western Blot, Human)
• W Shi, A Xianyu, Z Han, X Tang, Z Li, H Zhong, T Mao, K Huang, SH Shi Ontogenetic establishment of order-specific nuclear organization in the mammalian thalamus Nat. Neurosci, 2017-02-27;0(0):. 2017-02-27 [PMID: 28250409] (IHC, Mouse)
• A Shiraishi, K Muguruma, Y Sasai Generation of thalamic neurons from mouse embryonic stem cells Development, 2017-02-20;0(0):. 2017-02-20 [PMID: 28219951] (ICC, IHC, Mouse)
• Vue TY, Aaker J, Taniguchi A Characterization of progenitor domains in the developing mouse thalamus. J. Comp. Neurol., 2007-11-01;505(1):73-91. 2007-11-01 [PMID: 17729296] (IHC-Fr, Mouse)

Bioinformatics

• Gene Symbol: OLIG3
• Uniprot:
  • Q7RTU3()