OA1 Antibody - BSA Free

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Immunohistochemistry-Paraffin: OA1 Antibody [NLS2128] - Analysis of anti-GPR143 antibody with human brain, glioblastoma.
Immunohistochemistry-Paraffin: OA1 Antibody [NLS2128] - Analysis of anti-GPR143 antibody with eye, retina.

Product Details

Summary
Reactivity Hu, PmSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

OA1 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from C-terminus of human OA1.
Epitope
C-Terminus
Specificity
Human GPR143. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Primate (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR143
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5 - 10 ug/ml
Application Notes
.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Monkey (88%), Marmoset (88%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for OA1 Antibody - BSA Free

  • G protein-coupled receptor 143
  • G-protein coupled receptor 143
  • NYS6
  • OA1Ocular albinism type 1 protein
  • ocular albinism 1 (Nettleship-Falls)

Background

Ocular albinism 1 (Nettleship-Falls; OA1) is an Orphan-U GPCR with an unknown ligand. Ocular albinism type 1 (OA1) is an inherited disorder characterized by severe reduction of visual acuity, photophobia, and retinal hypopigmentation. Ocular albinism type 1 protein is a conserved integral membrane protein with seven transmembrane domains. Misfolding of the OA1 protein has been suggested as a major pathogenic mechanism in OA1. OA1 protein expression has been documented in the eye and in epidermal melanocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Additional OA1 Products

Research Areas for OA1 Antibody (NLS2128)

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Blogs on OA1

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Bioinformatics

Gene Symbol GPR143
Entrez