NK2R Antibody

Product Discontinued

NK2R Antibody Summary

• Immunogen: Peptide with sequence STRVNRCHTKET corresponding to internal region according to NP_001048.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: TACR2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:2000
• Application Notes: WB: Preliminary experiments in human duodenum, Ileum, heart and lung lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for NK2R Antibody

• Neurokinin A Receptor
• Neurokinin-2 Receptor
• NK2R
• NK2RNK-2 receptor
• NKNAR
• NKNARseven transmembrane helix receptor
• SKR
• SKRneurokinin 2 receptor
• Substance K Receptor
• substance-K receptor
• TAC2R
• TAC2Rsubstance K receptor
• Tachykinin Receptor 2
• tachykinin receptor 2NK-2R
• TACR2

Background

Nucleostemin is a protein found in the nucleoli of embryonic stem cells, adult CNS stem cells, primitive cells in the bone marrow and cancer cells. It is not in the differentiated cells of most adult tissues. It has been suggested to play a role in controlling the cell-cycle progression in stem cells and cancer cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for NK2R Antibody (NBP1-00244)(1)

Publication using NBP1-00244

• Miotto D, Boschetto P, Cavallesco G et al. Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Histopathology 2007-07-01 [PMID: 17532769]

Bioinformatics

• Gene Symbol: TACR2
• Entrez:
  • 6865(Human)
• Uniprot:
  • NP_001048.2(Human)