NIPSNAP1 Antibody - BSA Free

Western Blot: NIPSNAP1 Antibody [NBP1-76888] - Human brain tissue lysate with NIPSNAP antibody at (A) 0.5 and (B) 1 ug/ml.

Immunohistochemistry: NIPSNAP1 Antibody [NBP1-76888] - Immunohistochemical staining of human brain tissue using Nipsnap antibody at 2.5 ug/mL.

Immunofluorescence: NIPSNAP1 Antibody [NBP1-76888] - Human brain tissue with nipsnap antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC, IHC-P, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

NIPSNAP1 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 19 amino acid synthetic peptide from near the center of human NIPSNAP. The immunogen is located within amino acids 130 - 180 of NIPSNAP. Amino Acid Squence: CMNKLKNNKEYLEFRRERT
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NIPSNAP1
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunofluorescence 20 ug/ml
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 0.5-1 ug/ml
• Control Peptide:

  NIPSNAP1 Peptide (NBP1-76888PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Peptide affinity purified

Alternate Names for NIPSNAP1 Antibody - BSA Free

• nipsnap homolog 1 (C. elegans)
• NIPSNAP, C. elegans, homolog 1,4-nitrophenylphosphatase domain and non-neuronal SNAP25-like 1
• NipSnap1
• protein NipSnap homolog 1

Background

NIPSNAP is a member of an evolutionarily well conserved gene family and has a strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. Recent studies have indicated that NIPSNAP is involved in the regulation of the Ca2+-selective transient receptor potential vanilloid channel 6 (TRPV6). NIPSNAP1 associates with TRPV6 at the plasma membrane and inhibits TRPV6 currents. Other studies show that NIPSNAP's expression is reduced in the phenylketonuria (PKU) mouse brain, suggesting that NIPSNAP may play a role in memory.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NIPSNAP1
• Uniprot:
  • NP_003625(Human)