Nectin-3/PVRL3 Antibody

Western Blot: Nectin-3/PVRL3 Antibody [NBP1-45736] - Aanalysis of Nectin-3 expression in lysate from rat kidney (Lane 1) and 3T3 cells (Lane 2).

Product Discontinued

Nectin-3/PVRL3 Antibody Summary

• Description: This product is manufactured by Abcam and distributed by Novus Biologicals. (Abcam Catalog Number: ab63931)
• Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 536 of mouse Nectin-3.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NECTIN3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5 - 4 ug/mL

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2 ), 5 mM EDTA, 30% glycerol, 0.5% BSA
• Preservative: 0.03% Proclin 300
• Concentration: 0.5 mg/ml
• Purity: Affinity purified

Alternate Names for Nectin-3/PVRL3 Antibody

• CD113 antigen
• CD113
• CDw113FLJ90624
• DKFZp566B0846
• nectin 3
• Nectin3
• Nectin-3
• poliovirus receptor-related 3
• poliovirus receptor-related protein 3
• PPR3
• PRR3CD113
• PVRL3
• PVRR3

Background

Nectins (e.g., PVRL1; MIM 600644) are immunoglobulin-like adhesion molecules that interact with afadin (AF6; MIM 159559). Afadin is an actin filament-binding protein that connects nectins to the actin cytoskeleton. The nectin-afadin system organizes adherens junctions cooperatively with the cadherin (see MIM 192090)-catenin (see MIM 116805) system in epithelial cells.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: NECTIN3
• Entrez:
  • 25945(Human)
• Uniprot:
  • Q9NQS3()