NCOA5 Antibody Summary
The immunogen recognized by this antibody maps to a region between residue 525 and the C-terminus (residue 579) of human Nuclear Receptor Coactivator 5 (Coactivator Independent of AF-2) using the numbering given in entry NP_066018.1 (GeneID 57727).
Immunogen affinity purified
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- Immunohistochemistry 1:100-1:500
- Immunohistochemistry-Paraffin 1:100-1:500
- Immunoprecipitation 2-5 ug/mg lysate
- Western Blot 1:2000-1:10000
Epitope retrieval with Tris-EDTA pH9.0 is recommended for FFPE tissue sections.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Packaging, Storage & Formulations
Store at 4C. Do not freeze.
TBS and 0.1% BSA
0.09% Sodium Azide
Immunogen affinity purified
Alternate Names for NCOA5 Antibody
- Coactivator independent of AF-2
- nuclear receptor coactivator 5
NCOA5 is a nuclear receptor coregulator that can have both coactivator and corepressor functions. It interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the orphan nuclear receptor NR1D2. It Is also involved in the coactivation of nuclear steroid receptors (ER) as well as the corepression of MYC/c-myc in response to 17-beta-estradiol (E2).
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
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