Nav1.5 Peptide

• Reactivity: Hu
• Applications: AC

Nav1.5 Peptide Summary

• Description: A peptide to SCN5A.
• Protein/Peptide Type: Peptide
• Gene: SCN5A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This antibody is useful for Peptode ELISA and Western Blot. Preliminary experiments in ysates of Human Breast and Heart tissues gave no specific signal but low background.

Reactivity Notes

Human, mouse, rat, dog and cow.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Peptide dissolved in dH2O. Contains no BSA.
• Preservative: No Preservative

Alternate Names for Nav1.5 Peptide

• cardiac sodium channel alpha subunit
• cardiac tetrodotoxin-insensitive voltage-dependent sodium channel alpha subunit
• CDCD2VF1
• HB1sodium channel, voltage-gated, type V, alpha (long QT syndrome 3)
• HB2
• HBBD
• HH1CMD1E
• ICCD
• IVF
• LQT3SSS1CMPD2
• Nav1.5
• PFHB1
• SCN5A
• Sodium channel protein cardiac muscle subunit alpha
• sodium channel protein type 5 subunit alpha
• sodium channel protein type V alpha subunit
• Sodium channel protein type V subunit alpha
• sodium channel, voltage-gated, type V, alpha subunit
• Voltage-gated sodium channel subunit alpha Nav1.5

Background

Nav1.5 is encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. The encoded protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in two transcript variants encoding separate isoforms which differ by a single amino acid. Mutation nomenclature has been assigned with respect to the longer isoform. This antibody is expected to recognise both reported isoforms (NP_000326 and NP_932173).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: SCN5A