Natriuretic Peptide Receptor C Antibody

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-90163] - Staining in human kidney and cerebral cortex tissues.. Corresponding NPR3 RNA-seq data are presented for the same tissues.

Western Blot: Natriuretic Peptide Receptor C Antibody [NBP1-90163] - Analysis in human cell line HeLa and human cell line CACO-2.

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-90163] - Staining of human fallopian tube shows moderate to strong membranous positivity in smooth muscle cells.

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-90163] - Staining of human cerebral cortex shows no positivity in neurons as expected.

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-90163] - Staining of human kidney shows moderate to strong membranous positivity in cells in glomeruli.

Immunohistochemistry-Paraffin: Natriuretic Peptide Receptor C Antibody [NBP1-90163] - Staining of human endometrium shows moderate to strong membranous positivity in smooth muscle cells.

Product Discontinued

Natriuretic Peptide Receptor C Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: GFQHKDSEYSHLTRVAPAYAKMGEMMLALFRHHHWSRAALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSIYSFDETKDLDLEDIVRNIQASERVVIMCASSDTIRSIMLVAHRHGMTSGDYAFFNIELFNSSSYGDGSW
• Predicted Species: Mouse (93%), Rat (92%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: NPR3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Reactivity Notes

Reactivity reported in scientific literature (PMID: 22134537)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Natriuretic Peptide Receptor C Antibody

• ANP-C
• ANPR-C
• ANPRCFLJ14054
• Atrial natriuretic peptide clearance receptor
• atrial natriuretic peptide receptor 3
• Atrial natriuretic peptide receptor type C
• C5orf23
• chromosome 5 open reading frame 23
• GUCY2B
• lgj
• natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptidereceptor C)
• NPR3
• NPRC
• NPR-C
• stri

Background

The family of natriuretic peptides (see MIM 108780) elicit a number of vascular, renal, and endocrine effects that are important in the maintenance of blood pressure and extracellular fluid volume. These effects are mediated by specific binding of the peptides to cell surface receptors in the vasculature, kidney, adrenal, and brain.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Natriuretic Peptide Receptor C Antibody (NBP1-90163)(1)

Publication using NBP1-90163

• Taylor MD, Northcott PA, Korshunov A et al. Molecular subgroups of medulloblastoma: the current consensus. Acta Neuropathol 2012-04-01 [PMID: 22134537]

Bioinformatics

• Gene Symbol: NPR3