Myosin Phosphatase [p Thr696] Antibody

Images

 
There are currently no images for Myosin Phosphatase Antibody (NBP2-13184).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

Myosin Phosphatase [p Thr696] Antibody Summary

Immunogen
Synthetic phosphopeptide corresponding to residues surroundiing Thr696 of human MYPT1.
Modification
p Thr696
Specificity
Recognizes endogenous levels of MYPT1, phosphorylated at (thr696)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP1R12A
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000
Application Notes
Suitable for use in Western Blot. Other applications not tested.

Reactivity Notes

Human, Monkey, mouse, rat

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
10mM Sodium HEPES (pH 7.5), 0.15M NaCl, 0.1 mg/ml BSA and 50% Glycerol
Preservative
No Preservative
Purity
Protein A purified

Alternate Names for Myosin Phosphatase [p Thr696] Antibody

  • MBSmyosin phosphatase, target subunit 1
  • MGC133042
  • Myosin phosphatase target subunit 1
  • Myosin phosphatase-targeting subunit 1
  • MYPT1protein phosphatase 1 regulatory subunit 12A
  • protein phosphatase 1, regulatory (inhibitor) subunit 12A
  • Protein phosphatase myosin-binding subunit

Background

Protein phosphatase 1 (PP1) is a ubiquitous eukaryotic protein serine/threonine phosphatase involved in the regulation of various cell functions. Substrate specificity is determined by the binding of a regulatory subunit to the PP1 catalytic subunit (PP1c). It is estimated that over fifty different regulatory subunits exist (1). The myosin phosphatase holoenzyme is composed of three subunits: the PP1 catalytic subunit (PP1c), a targeting/regulatory subunit (MYPT/myosin-binding subunit of myosin phosphatase) and a 20kD subunit of unknown function (M20). MYPT binding to PP1cd alters the conformation of the catalytic cleft and increases enzyme activity and specificity (2). Two MYPT isoforms that are 61% identical have been described. MYPT1 is widely expressed while MYPT2 expression appears to be exclusive to heart and brain (3). Related family members also include MBS85, MYPT3 and TIMAP (4).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NBP2-37897
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-01462
Species: Hu
Applications: WB, Flow, ICC/IF
NBP1-47602
Species: Bv
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IP
NBP1-80073
Species: Hu, Rt
Applications: WB, IHC, IHC-P
NB100-91273
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NB110-89456
Species: Hu
Applications: WB, ELISA, IHC, IHC-Fr, IHC-P
NBP1-84168
Species: Hu
Applications: IHC, IHC-P
NB100-624
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
NBP1-86648
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-87744
Species: Hu
Applications: WB, IHC, IHC-P
NBP2-34260
Species: Hu, Mu, Po, Bv, Rb
Applications: WB, Flow, ICC/IF, IHC-Fr, IHC-P, IP, PAGE
NBP1-31348
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-22203
Species: Hu, Mu, Rt, Mk
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NLS1071
Species: Hu
Applications: IHC-P
H00085366-M01
Species: Hu
Applications: WB, ELISA, RNAi
NBP2-02521
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-13184
Species: Hu
Applications: WB

Publications for Myosin Phosphatase Antibody (NBP2-13184) (0)

There are no publications for Myosin Phosphatase Antibody (NBP2-13184).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Myosin Phosphatase Antibody (NBP2-13184) (0)

There are no reviews for Myosin Phosphatase Antibody (NBP2-13184). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for Myosin Phosphatase Antibody (NBP2-13184) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional Myosin Phosphatase Products

Bioinformatics Tool for Myosin Phosphatase Antibody (NBP2-13184)

Discover related pathways, diseases and genes to Myosin Phosphatase Antibody (NBP2-13184). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for Myosin Phosphatase Antibody (NBP2-13184)

Discover more about diseases related to Myosin Phosphatase Antibody (NBP2-13184).
 

Pathways for Myosin Phosphatase Antibody (NBP2-13184)

View related products by pathway.

PTMs for Myosin Phosphatase Antibody (NBP2-13184)

Learn more about PTMs related to Myosin Phosphatase Antibody (NBP2-13184).
 

Research Areas for Myosin Phosphatase Antibody (NBP2-13184)

Find related products by research area.

Blogs on Myosin Phosphatase

There are no specific blogs for Myosin Phosphatase, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Myosin Phosphatase [p Thr696] Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol PPP1R12A