Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

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Immunohistochemistry-Paraffin: Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody [NB100-58977] - Analysis of anti-CHRM3 / M3 antibody with human brain, cortex at concentration 10 ug/ml.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody Summary

Immunogen
Synthetic 16 amino acid peptide from 3rd cytoplasmic domain of human CHRM3 / M3.
Epitope
3rd cytoplasmic domain of human
Specificity
Human CHRM3 / M3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHRM3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100 - 1:2000
  • Immunohistochemistry-Paraffin 10 ug/ml
Positive Control
Muscarinic Acetylcholine Receptor M3/CHRM3 Lysate (NBL1-09175)

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Chimpanzee (100%), Gorilla (100%), Orangutan (94%), Gibbon (88%), Monkey (88%), Marmoset (88%), Panda (88%), Equine (88%), Porcine (88%), Elephant (81%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Muscarinic Acetylcholine Receptor M3/CHRM3 Antibody

  • cholinergic receptor, muscarinic 3
  • CHRM3
  • HM3
  • m3 muscarinic receptor
  • mAChR M3
  • muscarinic acetylcholine receptor M3

Background

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 3 controls smooth muscle contraction and its stimulation causes secretion of glandular tissue.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol CHRM3
Entrez