mu Opioid R/OPRM1 Antibody

Images

 
Western Blot: mu Opioid R/OPRM1 Antibody [NBP1-31180] - Sample(30 ug of whole cell lysate) A:A431 B:H1299 7.5% SDS PAGE, antibody diluted at 1:500.
Immunohistochemistry-Paraffin: mu Opioid R/OPRM1 Antibody [NBP1-31180] - Cal27 xenograft, using mu Opioid receptor antibody at 1:500 dilution. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min] - Paraffin-embedded ...read more

Product Details

Summary
Reactivity Hu, RMSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

mu Opioid R/OPRM1 Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human mu Opioid receptor. The exact sequence is proprietary.
Localization
Cell membrane, Multi-pass membrane protein
Predicted Species
Rhesus Macaque (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPRM1
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Application Notes
Use in ICC/IF reported in scientific literature (PMID: 22591368). Use in FLOW reported in scientific literature (PMID: 23751259).
Theoretical MW
45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
mu Opioid R/OPRM1 Knockout HeLa Cell Lysate
Reviewed Applications
Read 1 Review rated 5
using
NBP1-31180 in the following applications:

Publications
Read Publications using
NBP1-31180 in the following applications:

Reactivity Notes

Expected cross reactivity based on sequence homology: Pig (86%), Chimpanzee (86%), Bovine (86%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol
Preservative
0.01% Thimerosal
Purity
Antigen Affinity-purified

Alternate Names for mu Opioid R/OPRM1 Antibody

  • hMOP
  • KIAA0403
  • LMOR
  • MOP
  • mOpioidR
  • MOR
  • MOR1
  • M-OR-1
  • MOR-1
  • MOR1MOR
  • Mu opiate receptor
  • mu Opioid R
  • Mu opioid receptor
  • mu-type opioid receptor
  • opioid receptor, mu 1
  • OPRM
  • OPRM1

Background

Opioid receptors are the membrane proteins that mediate the pain-relieving effect of opioid drugs, such as morphine and fentanyl as well as endogenous opioid peptides enkephalins and endorphins. The effects of opiates are mediated through opioid receptors located on the plasma membrane of neurons and other peripheral cells. There are at least 3 types of opioid receptors, mu, kappa and delta, each with a distinct pharmacologic profile (1). The endogenous opioid system is involved in stress responses, in the regulation of the experience of pain, and in the action of analgesic opiate drugs. The activation of the mu-opioid receptor system was associated with reductions in the sensory and affective ratings of the pain experience, with distinct neuroanatomical involvements. Data demonstrate the central role of the mu-opioid receptors and their endogenous ligands in the regulation of sensory and affective components of the pain experience (2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for mu Opioid R/OPRM1 Antibody (NBP1-31180)(3)

Review for mu Opioid R/OPRM1 Antibody (NBP1-31180) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Rat.

Reviews using NBP1-31180:
Filter by Applications
WB
(1)
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Filter by Species
Rat
(1)
All Species
Images Ratings Applications Species Date Details
Western Blot mu Opioid R/OPRM1 NBP1-31180
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reviewed by:
Anonymous
WB Rat 02/21/2015
View

Summary

ApplicationWestern Blot
SpeciesRat
Lot39897
Special ApplicationsThe specie was rated a 5 because the failure to get signals may not be because the product is bad. To our knowledge, this is the first time testing the product in rats and thus, it may just not be reactive in the specie.
FileView PDF

Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for mu Opioid R/OPRM1 Antibody (NBP1-31180) (0)

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for mu Opioid R/OPRM1 Antibody (NBP1-31180)

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Recent Reviews

5
5
1
4
0
3
0
2
0
1
0

Anonymous
02/21/2015
Application: WB
Species: Rat

Bioinformatics

Gene Symbol OPRM1