Mouse YM1/Chitinase 3-like 3 DuoSet ELISA, 15 Plate

• Reactivity: Mu
• Applications: ELISA
• Conjugate: Biotin

Mouse YM1/Chitinase 3-like 3 DuoSet ELISA, 15 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: Chil3

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse YM1/Chitinase 3-like 3 DuoSet ELISA, 15 Plate

• AI505981
• CHI3L3
• Chitinase 3 like 3
• Chitinase 3-like 3
• ECF-L
• YM1

Background

Chitinase 3-like 3, also known as ECF-L and Ym1, is a secreted 377 amino acid lectin that binds heparin and GlcN oligomers. It is produced primarily by macrophages during inflammation. ECF-L shares homology with chitinase family proteins, but lacks enzymatic activity.

Publications for YM1/Chitinase 3-like 3 (DY2446)(12)

Publications using DY2446

• L Ho, A Yip, F Lao, F Botelho, CD Richards RELMalpha is Induced in Airway Epithelial Cells by Oncostatin M Without Requirement of STAT6 or IL-6 in Mouse Lungs In Vivo Cells, 2020-05-27;9(6):. 2020-05-27 [PMID: 32471168] (Mouse, Transgenic Mouse)
• AL Chenery, R Alhallaf, Z Agha, J Ajendra, JE Parkinson, MM Cooper, BHK Chan, RM Eichenberg, LA Dent, AAB Robertson, A Kupz, D Brough, A Loukas, TE Sutherland, JE Allen, PR Giacomin Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung J. Immunol., 2019-10-04;203(10):2724-2734. 2019-10-04 [PMID: 31586037] (Mouse)
• H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury JCI Insight, 2019-02-21;0(0):. 2019-02-21 [PMID: 30676324] (Mouse)
• M Becerra-Dí, AB Strickland, A Keselman, NM Heller Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation J. Immunol., 2018-10-10;0(0):. 2018-10-10 [PMID: 30305328] (Mouse)
• C Draijer, P Robbe, CE Boorsma, MN Hylkema, BN Melgert Dual role of YM1+ M2 macrophages in allergic lung inflammation Sci Rep, 2018-03-23;8(1):5105. 2018-03-23 [PMID: 29572536] (Mouse)
• H Cui, S Banerjee, S Guo, N Xie, G Liu IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages J. Immunol., 2018-03-21;0(0):. 2018-03-21 [PMID: 29563175] (Mouse)
• G Coakley, JL McCaskill, JG Borger, F Simbari, E Robertson, M Millar, Y Harcus, HJ McSorley, RM Maizels, AH Buck Extracellular Vesicles from a Helminth Parasite Suppress Macrophage Activation and Constitute an Effective Vaccine for Protective Immunity Cell Rep, 2017-05-23;19(8):1545-1557. 2017-05-23 [PMID: 28538175] (Mouse)
• SJ Van Dyken, HE Liang, RP Naikawadi, PG Woodruff, PJ Wolters, DJ Erle, RM Locksley Spontaneous Chitin Accumulation in Airways and Age-Related Fibrotic Lung Disease Cell, 2017-04-20;169(3):497-509.e13. 2017-04-20 [PMID: 28431248] (Mouse)
• IL-33 delivery induces serous cavity macrophage proliferation independent of interleukin-4 receptor alpha Eur J Immunol, 2016-10-01;0(0):. 2016-10-01 [PMID: 27592711] (Mouse)
• Larson-Casey J, Murthy S, Ryan A, Carter A Modulation of the mevalonate pathway by akt regulates macrophage survival and development of pulmonary fibrosis. J Biol Chem, 2014-11-05;289(52):36204-19. 2014-11-05 [PMID: 25378391] (Mouse)
• McSorley H, Blair N, Smith K, McKenzie A, Maizels R Blockade of IL-33 release and suppression of type 2 innate lymphoid cell responses by helminth secreted products in airway allergy. Mucosal Immunol, 2014-02-05;7(5):1068-78. 2014-02-05 [PMID: 24496315] (Mouse)
• Louten J, Mattson JD, Malinao MC, Li Y, Emson C, Vega F, Wardle RL, Van Scott MR, Fick RB, McClanahan TK, de Waal Malefyt R, Beaumont M Biomarkers of disease and treatment in murine and cynomolgus models of chronic asthma. Biomark Insights, 2012-07-10;7(0):87-104. 2012-07-10 [PMID: 22837640] (Mouse)

Bioinformatics

• Gene Symbol: Chil3