Mouse DPPIV/CD26 DuoSet ELISA, 15 Plate



Product Details

Reactivity MuSpecies Glossary
Applications ELISA

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Mouse DPPIV/CD26 DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DY954.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse DPPIV/CD26 DuoSet ELISA, 15 Plate

  • ADCP-2
  • Adenosine deaminase complexing protein 2TP103
  • CD26 antigen
  • CD26
  • CD26T-cell activation antigen CD26
  • dipeptidyl peptidase 4
  • Dipeptidyl peptidase IV
  • dipeptidylpeptidase 4
  • dipeptidyl-peptidase 4
  • dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2)
  • DPP4
  • EC


DPPIV/CD26 is a serine exopeptidase that is expressed as a noncovalent homodimer on the surface of epithelial cells, endothelial cells, and activated lymphocytes. It regulates multiple aspects of immune and endocrine function by cleaving Xaa-Pro or Xaa-Ala dipeptides from the N-terminus of a wide variety of chemokines (CCL4 and 5, CXCL6, 9, 10, 11, and 12), growth factors (GM-CSF, IL-3), and peptide hormones (Glucagon, Glucagon-like Peptides 1 and 2, GIP, GHRH, Procalcitonin, Neuropeptide Y, and Substance P). DPPIV interacts in cis with Adenosine Deaminase on T cells, in trans with Caveolin-1 on antigen presenting cells, and it serves as a cell entry coreceptor for HIV and coronavirus. It provides costimulatory proliferation and activation signals to both CD4+ and CD8+ T cells. A soluble form of DPPIV can be proteolytically shed from adipocytes, leading to insulin resistance in adipocytes and skeletal muscle.

Publications for DPPIV/CD26 (DY954)(8)

We have publications tested in 1 confirmed species: Mouse.

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Showing Publications 1 - 8 of 8.
Publications using DY954 Applications Species
NA Trzaskalsk, B Vulesevic, MA Nguyen, N Jeraj, E Fadzeyeva, NM Morrow, CA Locatelli, N Travis, AA Hanson, JR Nunes, C O'Dwyer, JN Van der Ve, I Lorenzen-S, R Seymour, SM Pulente, AC Clément, AM Crawley, RL Jacobs, MA Doyle, CL Cooper, KH Kim, MD Fullerton, EE Mulvihill Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, glucose production, and its absence alters liver disease progression JCI Insight, 2023-01-24;0(0):. 2023-01-24 [PMID: 36472923] (Mouse) Mouse
R Kamakura, GS Raza, A Prasannan, J Walkowiak, KH Herzig Dipeptidyl peptidase 4 and GLP-1 interplay in STC-1 and GLUTag cell lines Peptides, 2020-09-28;0(0):170419. 2020-09-28 [PMID: 32998057] (Mouse) Mouse
LL Baggio, EM Varin, JA Koehler, X Cao, Y Lokhnygina, SR Stevens, RR Holman, DJ Drucker Plasma levels of DPP4 activity and sDPP4 are dissociated from inflammation in mice and humans Nat Commun, 2020-07-28;11(1):3766. 2020-07-28 [PMID: 32724076] (Mouse) Mouse
S Saussentha, M Ouni, C Baumeier, K Schwerbel, P Gottmann, S Christmann, T Laeger, A Schürmann Epigenetic regulation of hepatic Dpp4 expression in response to dietary protein J. Nutr. Biochem., 2018-10-13;63(0):109-116. 2018-10-13 [PMID: 30359860] (Mouse) Mouse
M Rödiger, MW Werno, I Wilhelmi, C Baumeier, D Hesse, N Wettschure, S Offermanns, K Song, M Krau beta , A Schürmann Adiponectin release and insulin receptor targeting share trans-Golgi-dependent endosomal trafficking routes Mol Metab, 2017-11-22;0(0):. 2017-11-22 [PMID: 29203237] (Mouse) Mouse
C Baumeier, L Schlüter, S Saussentha, T Laeger, M Rödiger, SA Alaze, L Fritsche, HU Häring, N Stefan, A Fritsche, RW Schwenk, A Schürmann Elevated hepatic DPP4 activity promotes insulin resistance and non-alcoholic fatty liver disease Mol Metab, 2017-08-04;6(10):1254-1263. 2017-08-04 [PMID: 29031724] (Mouse) Mouse
Barreira da Silva R, Laird M, Yatim N, Fiette L, Ingersoll M, Albert M Dipeptidylpeptidase 4 inhibition enhances lymphocyte trafficking, improving both naturally occurring tumor immunity and immunotherapy. Nat Immunol, 2015-06-15;16(8):850-8. 2015-06-15 [PMID: 26075911] (Mouse) Mouse
Pang , Zhengda, Nakagami , Hironori, Osako , Mariana, Koriyama , Hiroshi, Nakagami , Futoshi, Tomioka , Hideki, Shimamura , Munehisa, Kurinami , Hitomi, Takami , Yoichi, Morishita , Ryuichi, Rakugi , Hiromi Therapeutic vaccine against DPP4 improves glucose metabolism in mice. Proc Natl Acad Sci U S A, 2014-03-17;111(13):E1256-63. 2014-03-17 [PMID: 24639549] (Mouse) Mouse

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Gene Symbol Dpp4