MKP-1/DUSP1 Antibody (4H7)

Images

 
Sandwich ELISA: MKP-1/DUSP1 Antibody (4H7) [H00001843-M02] - Detection limit for recombinant GST tagged DUSP1 is 0.3 ng/ml as a capture antibody.
Proximity Ligation Assay: MKP-1/DUSP1 Antibody (4H7) [H00001843-M02] - Analysis of protein-protein interactions between MAPK3 and DUSP1. HeLa cells were stained with anti-MAPK3 rabbit purified polyclonal 1:1200 and ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, PLA
Clone
4H7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

MKP-1/DUSP1 Antibody (4H7) Summary

Immunogen
DUSP1 (NP_004408 305 a.a. - 367 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
Specificity
DUSP1 - dual specificity phosphatase 1 (4H7)
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
DUSP1
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Proximity Ligation Assay
Application Notes
Antibody reactivity Against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control. FACS usage was reported in scientific literature.
Publications
Read Publication using
H00001843-M02 in the following applications:

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for MKP-1/DUSP1 Antibody (4H7)

  • CL100
  • CL100MAP kinase phosphatase 1
  • dual specificity phosphatase 1
  • Dual specificity protein phosphatase hVH1
  • DUSP1
  • EC 3.1.3.16
  • EC 3.1.3.48
  • HVH1
  • Mitogen-activated protein kinase phosphatase 1
  • MKP1
  • MKP-1
  • MKP-1dual specificity protein phosphatase 1
  • Protein-tyrosine phosphatase CL100
  • PTPN10
  • PTPN10serine/threonine specific protein phosphatase
  • VH1

Background

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MKP-1/DUSP1 Antibody (H00001843-M02)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: FLOW.


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FLOW
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Bioinformatics

Gene Symbol DUSP1
Entrez
Uniprot