MKP-1/DUSP1 Products

MKP-1/DUSP1 Antibody
MKP-1/DUSP1 Antibody
Species: Hu, Mu, Rt, Bv, Ca
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
MKP-1/DUSP1 Antibody (JJ0930) ...
MKP-1/DUSP1 Antibody (JJ0930)
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC-P, IP
Host: Rabbit Monoclonal
MKP-1/DUSP1 Antibody (408612) ...
MKP-1/DUSP1 Antibody (408612)
Species: Hu
Applications: IHC
Host: Rat Monoclonal
Formulation Catalog # Availability Price  
Recombinant Human MKP-1/DUSP1 ...
Recombinant Human MKP-1/DUSP1 GST ...
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human MKP-1/DUSP1 ...
Recombinant Human MKP-1/DUSP1 GST ...
Species: Hu
Applications: WB, ELISA, PA, AP
MKP-1/DUSP1 Recombinant Prote ...
MKP-1/DUSP1 Recombinant Protein An...
Species: Hu
Applications: AC


The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.


Entrez Human
Uniprot Human
Product By Gene ID 1843
Alternate Names
  • CL100MAP kinase phosphatase 1
  • dual specificity phosphatase 1
  • Dual specificity protein phosphatase hVH1
  • EC
  • EC
  • HVH1
  • Mitogen-activated protein kinase phosphatase 1
  • MKP1
  • MKP-1dual specificity protein phosphatase 1
  • Protein-tyrosine phosphatase CL100
  • PTPN10serine/threonine specific protein phosphatase
  • VH1

Research Areas for MKP-1/DUSP1

Find related products by research area and learn more about each of the different research areas below.

Cell Cycle and Replication
Protein Phosphatase

Bioinformatics Tool for MKP-1/DUSP1

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