MIS RII/AMHR2 Antibody (MIG7)

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-05491
    • Availability
      Product Discontinued

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MIS RII/AMHR2 Antibody (MIG7) Summary

Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with peptide 117-130 (NANYSHLPPPGSPG) conjugated with hsp70.
Specificity
Human cells bearing MISR, extracellular domain.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
AMHR2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Immunocytochemistry/Immunofluorescence

Reactivity Notes

Human and Rat

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein G purified

Alternate Names for MIS RII/AMHR2 Antibody (MIG7)

  • AMH type II receptor
  • AMHR2
  • AMHREC 2.7.11.30
  • AMHRII
  • C14
  • MIS RII
  • MISR2
  • MISRII
  • MISRIIMIS type II receptor
  • MRII
  • Muellerian hormone type II receptor
  • Muellerian hormone type-2 receptor
  • Mullerian hormone receptor, type II
  • Mullerian inhibiting substance type II receptor

Background

AMHR2 is a serine/threonine kinase with a single transmembrane domain belonging to the family of type II receptors for TGF-beta-related proteins that is expressed in fetal and adult gonads of both sexes. Anti-Mullerian hormone (AMH) and its receptor are involved in the regression of Mullerian ducts in male fetuses. Male sex differentiation is mediated by 2 discrete hormones produced by the fetal testis. Testosterone, produced by Leydig cells, virilizes the external genitalia and promotes prostatic growth; anti-Mullerian hormone (AMH) results in regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. A number of allelic variants of AMHR2 are associated with persistent mullerian duct syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol AMHR2
Entrez
Uniprot