Recombinant Human Meis homeobox 3 His Protein Summary
| Description |
A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-358 of Human Meis homeobox 3 Source: E.coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSMARRYDE LPHYPGIVDG PAALASFPET VPAVPGPYGP HRPPQPLPPG LDSDGLKREK DEIYGHPLFP LLALVFEKCE LATCSPRDGA GAGLGTPPGG DVCSSDSFNE DIAAFAKQVR SERPLFSSNP ELDNLMIQAI QVLRFHLLEL EKGKMPIDLV IEDRDGGCRE DFEDYPASCP SLPDQNNMWI RDHEDSGSVH LGTPGPSSGG LASQSGDNSS DQGDGLDTSV ASPSSGGEDE DLDQERRRNK KRGIFPKVAT NIMRAWLFQH LSHPYPSEEQ KKQLAQDTGL TILQVNNWFI NARRRIVQPM IDQSNRTGQG AAFSPEGQPI GGYTETQPHV AVRPPGSVGM SLNLEGEWHY L |
| Source |
E. coli |
| Protein/Peptide Type |
Recombinant Protein |
| Gene |
MEIS3 |
| Purity |
>85%, by SDS-PAGE |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays. |
| Theoretical MW |
41.4 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
20 mM Tris-HCl buffer (pH 8.0), 10% glycerol |
| Preservative |
No Preservative |
| Concentration |
1 mg/ml |
| Purity |
>85%, by SDS-PAGE |
Alternate Names for Recombinant Human Meis homeobox 3 His Protein
Background
MEIS3, also known as Homeobox protein Meis3, has 3 isoforms, a 375 amino acid isoform that is 41 kDa, a 421 amino acid isoform that is 46 kDa, and a 358 amino acid isoform that is 39 kDa, and is nucleus located. Little is currently known about its function. Studies are performed on the relationship of this protein to neuronitis. MEIS3 protein involvement has been observed with relation to HOXA13 in the regulation of transcription, DNA-dependent, negative regulation of apoptotic process, and positive regulation of protein kinase B signaling cascade pathways.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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