LH beta Antibody

Product Discontinued

LH beta Antibody Summary

• Immunogen: Highly purified human pituitary luteinizing hormone
• Specificity: Recognizes human luteinizing hormone, a gonadotrophic hormone found in the anterior lobe of the pituitary gland. Cross Reacts with:
  TSH 20%
  hCG 6%
  FSH 6%
  Prolactin <0.1%
  hPL <0.1%
  
  In an RIA, this antibody has an initial dilution of >1/50,000 in 125I overnight assay.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Gene: LHB
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Radioimmunoassay 1:100-1:2000

Reactivity Notes

Not yet tested in other species.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.09% Sodium Azide
• Purity: Protein G purified

Alternate Names for LH beta Antibody

• CGB4
• hLHB
• interstitial cell stimulating hormone, beta chain
• LH beta
• LHB
• LSH-B
• LSH-beta
• luteinizing hormone beta polypeptide
• luteinizing hormone beta subunit
• lutropin beta chain
• Lutropin beta
• lutropin subunit beta

Background

LH is a member of the glycoprotein hormone family. Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. LH is expressed in the pituitary gland and promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13.3. Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LHB
• Entrez:
  • 1081(Human)
• Uniprot:
  • P01229()