LAX1 Antibody

Western Blot: LAX1 Antibody [H00054900-B01P] - Analysis of LAX1 expression in transfected 293T cell line by LAX1 polyclonal antibody. Lane 1: LAX1 transfected lysate(43.78 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

LAX1 Antibody Summary

• Immunogen: LAX1 (NP_060243.2, 1 a.a. - 398 a.a.) full-length human protein. MDGVTPTLSTIRGRTLESSTLHVTPRSLDRNKDQITNIFSGFAGLLAILLVVAVFCILWNWNKRKKRQVPYLRVTVMPLLTLPQTRQRAKNIYDILPWRQEDLGRHESRSMRIFSTESLLSRNSESPEHVPSQAGNAFQEHTAHIHATEYAVGIYDNAMVPQMCGNLTPSAHCINVRASRDCASISSEDSHDYVNVPTAEEIAETLASTKSPSRNLFVLPSTQKLEFTEERDEGCGDAGDCTSLYSPGAEDSDSLSNGEGSSQISNDYVNMTGLDLSAIQERQLWVAFQCCRDYENVPAADPSGSQQQAEKDVPSSNIGHVEDKTDDPGTHVQCVKRTFLASGDYADFQPFTQSEDSQMKHREEMSNEDSSDYENVLTAKLGGRDSEQGPGTQLLPDE
• Specificity: LAX1 - lymphocyte transmembrane adaptor 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: LAX1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for LAX1 Antibody

• LAT-like membrane associated protein
• LAX1
• LAXFLJ20340
• Linker for activation of X cells
• lymphocyte transmembrane adapter 1
• lymphocyte transmembrane adaptor 1
• Membrane-associated adapter protein LAX

Background

Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for LAX1 Antibody (H00054900-B01P)(1)

Publication using H00054900-B01P

• Di Meo F, Iyer A, Akama K et al. A target discovery pipeline identified ILT3 as a target for immunotherapy of multiple myeloma Cell reports. Medicine 2023-07-18 [PMID: 37467717]

Bioinformatics

• Gene Symbol: LAX1
• Entrez:
  • 54900(Human)
• Uniprot:
  • NP_060243.2(Human)