LARP2 Antibody

Immunocytochemistry/Immunofluorescence: LARP2 Antibody [NB100-60945] - Analysis of paraformaldehyde fixed A431 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL), showing cytoplasmic staining. The nuclear stain is DAPI (blue). Negative control: Unimmunized goat IgG (10 ug/mL) followed by Alexa Fluor 488 secondary antibody (2 ug/mL).

Flow Cytometry: LARP2 Antibody [NB100-60945] - Analysis of paraformaldehyde fixed HepG2 cells (blue line), permeabilized with 0.5% Triton. Primary incubation overnight (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1 ug/mL). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.

• Reactivity: Hu
• Applications: ELISA, Flow, ICC/IF
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

LARP2 Antibody Summary

• Immunogen: Peptide with sequence C-QGVLHIPKKDLTDE corresponding to internal region according to NP_060548.2.
• Epitope: QGVLHIPKKDLTDE
• Specificity: This antibody is expected to recognize isoform 1 (NP_060548.2) only.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: LARP1B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 10 ug/mL
  • Immunocytochemistry/ Immunofluorescence 10 ug/mL
  • Peptide ELISA Detection limit 1:128000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for LARP2 Antibody

• DKFZp434K245
• DKFZp686E0316
• DKFZp686L13217
• FLJ10378
• La ribonucleoprotein domain family member 1B
• La ribonucleoprotein domain family member 2
• La ribonucleoprotein domain family, member 1B
• La ribonucleoprotein domain family, member 2
• la-related protein 1B
• La-related protein 2
• LARP2
• MGC117277
• MGC75174

Background

LARP2 contains domains found in the La related protein of Drosophila melanogaster. La motif-containing proteins are thought to be RNA-binding proteins, where the La motif and adjacent amino acids fold into an RNA recognition motif. The La motif is also found in proteins unrelated to the La protein. Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described. Additional splice variation has been identified but the full-length nature of these transcripts has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: LARP1B
• Entrez:
  • 55132(Human)
• Uniprot:
  • NP_060548.2(Human)