Laforin/EPM2A Antibody (4A12)

Images

 
Western Blot: Laforin/EPM2A Antibody (4A12) [H00007957-M01] - EPM2A monoclonal antibody (M01), clone 4A12. Analysis of EPM2A expression in PC-12.
Sandwich ELISA: Laforin/EPM2A Antibody (4A12) [H00007957-M01] - Detection limit for recombinant GST tagged EPM2A is approximately 3ng/ml as a capture antibody.

Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ELISA
Clone
4A12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

Laforin/EPM2A Antibody (4A12) Summary

Immunogen
EPM2A (NP_001018051, 101 a.a. - 199 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. GNGPHHDRCCTYNENNLVDGVYCLPIGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQVEHVTIKLKHELGITAVMNFQTEWDIV
Specificity
EPM2A - epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) (4A12)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
EPM2A
Purity
IgG purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for ELISA.
Publications
Read Publication using H00007957-M01.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Laforin/EPM2A Antibody (4A12)

  • EC 3.1.3.16
  • EC 3.1.3.48
  • epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
  • epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
  • EPM2
  • EPM2A
  • Lafora PTPase
  • Laforin
  • LAFPTPase
  • LD
  • LDE
  • MELF

Background

This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Laforin/EPM2A Antibody (H00007957-M01)(1)

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Bioinformatics

Gene Symbol EPM2A
Entrez
Uniprot