Kinesin 5A Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 0.2 mg/ml

Kinesin 5A Antibody Blocking Peptide Summary

• Description: A blocking peptide containing 20 amino acids near the center of human Kinesin 5A.

  Source: Synthetic

  (Accession #: Q12840)

• Source: Synthetic
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: KIF5A
• Purity: N/A

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NBP1-76817.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
• Preservative: 0.02% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: N/A

Alternate Names for Kinesin 5A Antibody Blocking Peptide

• D12S1889
• KIF5A variant protein
• kinesin family member 5A
• kinesin heavy chain isoform 5A
• Kinesin heavy chain neuron-specific 1
• kinesin, heavy chain, neuron-specific
• MY050
• Neuronal kinesin heavy chain
• NKHC1
• NKHCspastic paraplegia 10 (autosomal dominant)
• SPG10

Background

Kinesin 5A is part of a superfamily of microtubule-associated motor proteins involved in a variety of cellular processes including membranous organelle transport and cell division. Kinesin has been found in a variety of organisms and cell types and is subject to spatial and temporal regulation. These proteins have a modular structure including a conserved motor domain of approximately 350 amino acids, which is responsible for microtubule binding and ATP hydrolysis. In addition to the motor domain, subfamily members share common domain organization, exhibit sequence similarity, motility properties, and cellular functions outside of the motor domain. There are currently three known Kinesin 5 family members denoted as A, B, and C. Kinesin 5A and kinesin 5C appear to be exclusively neuronal, whereas kinesin 5B appears to be ubiquitous in its expression.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: KIF5A