Kallikrein 11 Antibody

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Western Blot: Kallikrein 11 Antibody [NB100-429] - Analysis of Kallikrein 11 at 1:500 dilution on 50 ug of LNCaP cell lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Kallikrein 11 Antibody Summary

Immunogen
Residues 68-82 [YIVHLGQHNLQKEEG] of the 35 kDa human hippostasin/KLK11protein. Sequence identity to mouse and rat: 86%.
Specificity
This is specific for Hippostasin/KLK11.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KLK11
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:1000
Application Notes
This antibody may be used for Western blot. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
31 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Kallikrein 11 Antibody

  • EC 3.4.21
  • EC 3.4.21.-
  • EC 3.4.21.4
  • Hippostasin
  • hK11
  • Kallikrein 11
  • kallikrein-related peptidase 11
  • KLK11
  • MGC33060
  • PRSS20kallikrein-11
  • Serine protease 20
  • TLSPhippostasin
  • Trypsin-like protease

Background

Hippostasin, also known as KLK11, is a kallikrein-like serine protease, which has two alternatively spliced isoforms, brain-type and prostate-type. Hippostasin plays a role in the prostate, including reproductive and/or tumorigenic functions. Elevated serum levels of hK11 were found in 70% of women with ovarian cancer and in 60% of men with prostate cancer. Analysis of the KLK11 biomarker in serum may aid in the diagnosis and monitoring of ovarian and prostatic carcinoma.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol KLK11
Entrez