ISCU Antibody

Western Blot: ISCU Antibody [H00023479-B01P] - Analysis of ISCU expression in transfected 293T cell line by ISCU polyclonal antibody. Lane 1: NIFUN transfected lysate(15.62 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

ISCU Antibody Summary

• Immunogen: NIFUN (NP_055116, 1 a.a. - 142 a.a.) full-length human protein. MVLIDMSVDLSTQVVDHYENPRNVGSLDKTSKNVGTGLVGAPACGDVMKLQIQVDEKGKIVDARFKTFGCGSAIASSSLATEWVKGKTVEEALTIKNTDIAKELCLPPVKLHCSMLAEDAIKAALADYKLKQEPKKGEAEKK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: ISCU
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: This antibody is useful for Western Blot, Functional

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for ISCU Antibody

• 2310020H20Rik
• HML
• hnifU
• iron-sulfur cluster assembly enzyme ISCU, mitochondrial
• iron-sulfur cluster scaffold homolog (E. coli)
• IscU iron-sulfur cluster scaffold homolog (E. coli)
• IscU iron-sulfur cluster scaffold homolog
• IscU
• ISU2
• MGC74517
• NIFU
• NifU-like N-terminal domain containing
• NifU-like N-terminal domain-containing protein
• NifU-like protein
• NIFUN

Background

Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ISCU
• Uniprot:
  • NP_055116(Human)