IRF2 Antibody

Immunocytochemistry/Immunofluorescence: IRF2 Antibody [NBP1-89433] - Staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: IRF2 Antibody [NBP1-89433] - Staining of human colon shows strong nuclear positivity in glandular cells.

Immunohistochemistry-Paraffin: IRF2 Antibody [NBP1-89433] - Staining of human skeletal muscle shows moderate to strong nuclear positivity in a subset of myocytes.

Immunohistochemistry-Paraffin: IRF2 Antibody [NBP1-89433] - Staining of human urinary bladder shows strong nuclear positivity in urothelial cells.

Immunohistochemistry-Paraffin: IRF2 Antibody [NBP1-89433] - Staining of human tonsil shows moderate nuclear positivity in lymphoid cells.

• Reactivity: Hu, Mu, Rt
• Applications: ICC/IF, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

IRF2 Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: SLPDIEEVKDKSIKKGNNAFRVYRMLPLSERPSKKGKKPKTEKEDKVKHIKQEPVESSLGLSNGVSDLSPEYAVLTSTIKNEVDSTVNIIVVGQSHLDSNIE
• Predicted Species: Mouse (94%), Rat (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: IRF2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  IRF2 Protein (NBP1-89433PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for IRF2 Antibody

• DKFZp686F0244
• interferon regulatory factor 2
• IRF2
• IRF-2

Background

IRF2 encodes interferon regulatory factor 2, a member of the interferon regulatory transcription factor (IRF) family. IRF2 competitively inhibits the IRF1-mediated transcriptional activation of interferons alpha and beta, and presumably other genes that employ IRF1 for transcription activation. However, IRF2 also functions as a transcriptional activator of histone H4.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IRF2