ING2 Antibody (AT39E5) [DyLight 488]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF
• Clone: AT39E5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

ING2 Antibody (AT39E5) [DyLight 488] Summary

• Immunogen: Recombinant human ING2 (1-280aa) purified from E. coli
• Isotype: IgG1b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: ING2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

0

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for ING2 Antibody (AT39E5) [DyLight 488]

• ING1Linhibitor of growth family, member 1-like
• ING1Lp
• Inhibitor of growth 1-like protein
• inhibitor of growth family, member 2
• inhibitor of growth protein 2
• p33ING2p32

Background

ING2 is similar to ING1, a tumor suppressor protein that can bind TP53, inhibit cell growth, and induce apoptosis. This protein binds phosphoinositides (PtdInPs) at its plant homeodomain (PHD) domain and it acts as a PtdInPs receptor. PtdInPs binding regulates the ability of this protein to activate TP53 and TP53-dependent apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ING2