IL-22R alpha 1 Antibody

Immunohistochemistry: IL-22 R alpha 1 Antibody [NB100-740] - Immunohistochemistry with CI0152 on paraffin section of human tonsil.

Immunohistochemistry: IL-22 R alpha 1 Antibody [NB100-740] - Immunohistochemistry with CI0152 on paraffin section of human spleen.

• Reactivity: Hu
• Applications: ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated

IL-22R alpha 1 Antibody Summary

• Immunogen: Synthetic peptide: DSGPEGTPDTVYSIEYKTYGERDWVAKK, corresponding to N terminal amino acids 42-70 of Human IL22 Receptor.
• Localization: Cell Membrane
• Specificity: IL22 Receptor
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IL22RA1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
• Application Notes: Immunohistochemistry-Paraffin: Perform heat mediated antigen retrieval via the pressure cooker method (with citrate buffer pH 6 or pH 8) before commencing with IHC staining protocol. See recommended protocol. The ELISA dilution is a minimum. Optimal dilutions/concentrations should be determined by the end user. Although not tested this antibody may be useful in Immunocytochemistry/immunoflourescence and Immunohistochemistry-Frozen.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA
• Preservative: 0.1% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for IL-22R alpha 1 Antibody

• CRF2-9
• CRF2-9interleukin 22 receptor
• Cytokine receptor class-II member 9
• Cytokine receptor family 2 member 9
• IL-22 R alpha 1
• IL-22 receptor subunit alpha-1
• IL22R alpha 1
• IL22R
• IL22R1
• IL22RA1
• IL-22Ra1
• IL-22R-alpha-1
• IL-TIF-R1
• interleukin 22 receptor, alpha 1
• interleukin-22 receptor subunit alpha-1
• zcytoR11

Background

The IL-22RA1 (also termed CRF29 and IL TIFR1 chain) is a new member of the class II cytokine receptor family. IL-22RA1 forms a complex with IL10 Receptor beta chain and mediates IL22 signaling. IL-22RA1 and its receptor activate the JAK/STAT signaling pathway. IL-22RA1 is expressed in normal liver and kidney and their cell lines HepG2 and TK10.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: IL22RA1
• Entrez:
  • 58985(Human)