IL-20 R beta/FNDC6 Antibody (20RNTC)

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Immunocytochemistry/ Immunofluorescence: FNDC6 Antibody (20RNTC) [NBP2-00466] - Immunofluorescent microscopy of fixed and permeabilized A375 cells using 10 ug/ml of Anti-Human/Mouse IL-20 Receptor 2 (IL-20Rb) Purified ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow, ICC/IF
Clone
20RNTC
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

IL-20 R beta/FNDC6 Antibody (20RNTC) Summary

Immunogen
The immunogen for this antibody is FNDC6 (IL-20R2).
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Rat
Gene
IL20RB
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 1-10 ug/ml
  • Immunocytochemistry/Immunofluorescence 1-10 ug/ml
Application Notes
This 20RNTC antibody has been tested by immunofluorescent staining and flow cytometric analysis of fixed and permeabilized A375 cells. This 20RNTC antibody has also been reported for use in immunocytochemistry and immunoblotting.

Reactivity Notes

Human, Mouse

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Aqueous, may contain carrier protein/stabilizer.
Preservative
0.09% Sodium Azide
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for IL-20 R beta/FNDC6 Antibody (20RNTC)

  • FNDC6
  • DIRS1
  • FNDC6
  • IL-20 R beta
  • IL20R beta
  • IL-20R2
  • IL20RB interleukin 20 receptor beta
  • IL20RB
  • IL-20Rb
  • MGC34923

Background

This 20RNTC monoclonal antibody recognizes mouse and human IL-20R2 (interleukin-20 receptor 2, IL-20Rb) in either of its two heterodimeric complexes formed by pairing with IL-20R1 or IL-22R1. IL-20R2 belongs to the class II cytokine receptor family that shares a characteristic pattern of cysteine, proline and tryptophan residues in the extracellular domain. IL-20R2 paired with IL-20R1 forms a receptor that binds IL-20, IL-19, or IL-24. IL-20R2 paired with IL22R1 forms a receptor that binds IL-20 or IL-24. The IL-20R complex signals primarily via the JAK-STAT pathway. IL-20R2 is found predominantly on cells of epithelial origin such as gut and skin and can be upregulated during inflammation. Immunofluorescent staining of A375 cells reveals a punctate staining pattern at the cell membrane, as well as diffuse, cytoplasmic staining that is likely associated with protein synthesis and transport in the endoplasmic reticulum and golgi.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP2-00466AF405
Alexa Fluor 488 Labeled NBP2-00466AF488
Alexa Fluor 647 Labeled NBP2-00466AF647
Alexa Fluor 700 Labeled NBP2-00466AF700
Allophycocyanin Labeled NBP2-00466APC
DyLight 350 Labeled NBP2-00466UV
DyLight 405 Labeled NBP2-00466V
DyLight 488 Labeled NBP2-00466G
DyLight 680 Labeled NBP2-00466FR
DyLight 755 Labeled NBP2-00466IR
PE Labeled NBP2-00466PE
PerCP Labeled NBP2-00466PCP

Additional IL-20 R beta/FNDC6 Products

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Bioinformatics

Gene Symbol IL20RB
Entrez