Human Meteorin-like/METRNL DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human Meteorin-like/METRNL DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details
• Gene: METRNL

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Meteorin-like/METRNL DuoSet ELISA, 5 Plate

• Meteorin like
• meteorin, glial cell differentiation regulator-like
• meteorin-like protein
• Meteorin-like
• METRNL
• MGC99788

Background

METRNL (Meteorin-like) is a cytoplasmic 30 kDa (predicted) member of the meteorin family of proteins. The name meteorin derives from the ability of the founding family member meteorin to transform glia into cells containing an extensive, meteor-like tail. It is expressed by neurons, and appears to function as a primer molecule that sets the stage for either cell differentiation or neurite outgrowth when it acts with Dclk1 and SerpinB1. Mature human METRNL is 266 amino acids (aa) in length (aa 46-311). It reportedly contains a signal sequence (aa 1-45), which suggests it may be secreted. Mature human and mouse METRNL share 79% aa sequence identity.

Publications for Meteorin-like/METRNL (DY7867-05)(6)

Publications using DY7867-05

• Joci?, J;Lu?i?, AT;Jovanovi?, I;Juriševi?, M;Stanisavljevi?, I;Stamenkovi?, B;Pavlovi?, S; Interleukin 41 As A Potential Predictor of Bio-Therapy Efficacy In Patients With Rheumatoid Arthritis: A Prospective Observational Study International journal of medical sciences 2024-09-30 [PMID: 39439456] (Human)
• X Wen, X Ding, X Chang, J Wang, Q Wang, J Liu, G Wang Elevated serum Meteorin-like levels in patients with hyperthyroidism BMC endocrine disorders, 2022-12-07;22(1):304. 2022-12-07 [PMID: 36476346] (Human)
• S Zhang, Y Lei, T Sun, Z Gao, Z Li, H Shen Elevated levels of Metrnl in rheumatoid arthritis: Association with disease activity Cytokine, 2022-09-07;159(0):156026. 2022-09-07 [PMID: 36084603] (Human)
• A Gholamreza, M Mohamadina, P Rahbarinej, S Fallah, SR Barez, L Setayesh, N Moradi, R Fadaei, E Chamani, T Tavakoli Characterization of the serum levels of Meteorin-like in patients with inflammatory bowel disease and its association with inflammatory cytokines Lipids Health Dis, 2020-10-30;19(1):230. 2020-10-30 [PMID: 33126870] (Human)
• SL Zheng, ZY Li, Z Zhang, DS Wang, J Xu, CY Miao Evaluation of Two Commercial�Enzyme-linked Immunosorbent Assay�Kits for the Detection of�Human Circulating Metrnl Chem. Pharm. Bull., 2018-02-02;0(0):. 2018-02-02 [PMID: 29398678] (Human)
• Li Z, Song J, Zheng S, Fan M, Guan Y, Qu Y, Xu J, Wang P, Miao C Adipocyte Metrnl Antagonizes Insulin Resistance Through PPARgamma Signaling. Diabetes, 2015-08-25;64(12):4011-22. 2015-08-25 [PMID: 26307585] (Human)

Bioinformatics

• Gene Symbol: METRNL