Human Matriptase/ST14 Catalytic Domain DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Conjugate: Biotin

Human Matriptase/ST14 Catalytic Domain DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA, 5 Plate

• EC 3.4.21
• Epithin
• HAI
• Matriptase
• Membrane-type serine protease 1
• MTSP1
• MT-SP1EC 3.4.21.109
• prostamin
• PRSS14
• Serine protease 14
• Serine protease TADG-15
• SNC19
• SNC19MTSP1
• ST14
• suppression of tumorigenicity 14 (colon carcinoma)
• suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
• suppressor of tumorigenicity 14 protein
• TADG15
• TADG-15
• TMPRSS14
• tumor associated differentially expressed gene 15 protein
• Tumor-associated differentially-expressed gene 15 protein

Background

Human matriptase, encoded by the ST14 (suppression of tumorogenicity 14) gene, is also known as tumor associated differentially expressed gene 15 protein/TADG-15), epithin, and membrane-type serine protease 1/MT-SP1. Predicted to have a significant role in tumor biology, matriptase may be a novel target for anti-cancer therapy. However, expressed in most human epithelia, matriptase is also important in several physiological processes. For example, it activates prostasin to initiate a protease cascade that is essential for epidermal differentiation, and it converts a single-chain IGFBP-rp1 into the two-chain form.