Human Matriptase/ST14 Catalytic Domain DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Conjugate: Biotin

Human Matriptase/ST14 Catalytic Domain DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Matriptase/ST14 Catalytic Domain DuoSet ELISA, 5 Plate

• EC 3.4.21
• Epithin
• HAI
• Matriptase
• Membrane-type serine protease 1
• MTSP1
• MT-SP1EC 3.4.21.109
• prostamin
• PRSS14
• Serine protease 14
• Serine protease TADG-15
• SNC19
• SNC19MTSP1
• ST14
• suppression of tumorigenicity 14 (colon carcinoma)
• suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
• suppressor of tumorigenicity 14 protein
• TADG15
• TADG-15
• TMPRSS14
• tumor associated differentially expressed gene 15 protein
• Tumor-associated differentially-expressed gene 15 protein

Background

Human matriptase, encoded by the ST14 (suppression of tumorogenicity 14) gene, is also known as tumor associated differentially expressed gene 15 protein/TADG-15), epithin, and membrane-type serine protease 1/MT-SP1. Predicted to have a significant role in tumor biology, matriptase may be a novel target for anti-cancer therapy. However, expressed in most human epithelia, matriptase is also important in several physiological processes. For example, it activates prostasin to initiate a protease cascade that is essential for epidermal differentiation, and it converts a single-chain IGFBP-rp1 into the two-chain form.

FAQs for Matriptase/ST14 (DY3946-05). (Showing 1 - 1 of 1 FAQ).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.