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HAF016). Specific bands were detected for Matriptase/ST14 at approximately 25 and 90 kDa (as indicated). This experiment was conducted under reducing conditions and using Western Blot Buffer Group 1." class="big_lightbox" target="_blank">
HAF016) in Milk-free Antibody Diluent (Catalog # 043-524). This experiment was conducted under reducing conditions and using the 12-230kDa separation system. Right: Simple Western electropherogram showing the same Sheep Anti-Human Matriptase/ST14 Catalytic Domain Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3946) tested at 10 µg/ml (blue line) and 50 µg/ml (green line) in the Ramos human Burkitt's lymphoma cell line." class="big_lightbox" target="_blank">
5-001-A, open histogram), followed by NorthernLights™ 557-conjugated Anti-Sheep IgG Secondary Antibody (NL010). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin." class="big_lightbox" target="_blank">
MAB002, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG F(ab')2Secondary Antibody (Catalog # F0102B). To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin." class="big_lightbox" target="_blank">
ST14 is encoded by this gene is an epithelial-derived, integral membrane serine protease. This protease forms a complex with the Kunitz-type serine protease inhibitor, HAI-1, and is found to be activated by sphingosine 1-phosphate. This protease has been shown to cleave and activate hepatocyte growth factor/scattering factor, and urokinase plasminogen activator, which suggest the function of this protease as an epithelial membrane activator for other proteases and latent growth factors. The expression of this protease has been associated with breast, colon, prostate, and ovarian tumors, which implicates its role in cancer invasion, and metastasis.
![Western Blot Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/images/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-western-blot-639192117844559380.jpg)
![N/A Matriptase/ST14 [Biotin]](http://images.novusbio.com/fullsize/dy3946-05_human-matriptase-st14-catalytic-domain-duoset-elisa-5-plate-2062024131610..png)
![Simple Western Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/images/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-simple-western-639192120819517655.jpg)
![Intracellular Staining by Flow Cytometry Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/Matriptase_AF3946_Flow_Cytometry_8218.jpg)
![Simple Western Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-41202412403548.jpg)
![Simple Western Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-41202412401222.jpg)
![Simple Western Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-41202412403545.jpg)
![Simple Western Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-4120241239322.jpg)
![Simple Western Matriptase/ST14 Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af3946_human-matriptase-st14-affinity-purified-polyclonal-ab-41202412394982.jpg)
