Human IFN-alpha 2/IFNA2 DuoSet ELISA, 5 Plate

• Reactivity: Hu
• Applications: ELISA
• Conjugate: Biotin

Human IFN-alpha 2/IFNA2 DuoSet ELISA, 5 Plate Summary

• Source: N/A
• Assay Type: Solid Phase Sandwich ELISA
• Inter-Assay: See PDF Datasheet for details
• Intra-Assay: See PDF Datasheet for details
• Spike Recovery: See PDF Datasheet for details
• Sample Volume: See PDF Datasheet for details

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: No significant interference observed with available related molecules.

Packaging, Storage & Formulations

• Storage: Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human IFN-alpha 2/IFNA2 DuoSet ELISA, 5 Plate

• alpha-2a interferon
• Ifa2
• IFNA
• IFNA2
• IFNA2a
• IFNA2b
• IFNA2c
• IFNAA
• IFNalpha 2
• IFN-alpha 2
• IFN-alpha-2
• IFN-alphaA
• INFA2
• interferon alpha 2b
• interferon alpha A
• interferon alpha-2
• Interferon alpha-A
• interferon, alpha 2
• LeIF A
• MGC125764
• MGC125765

Background

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Publications for IFN-alpha 2 (DY9345-05)(4)

Publications using DY9345-05

• Crawford, JD;Wang, H;Trejo-Zambrano, D;Cimbro, R;Talbot, CC;Thomas, MA;Curran, AM;Girgis, AA;Schroeder, JT;Fava, A;Goldman, DW;Petri, M;Rosen, A;Antiochos, B;Darrah, E; The XIST lncRNA is a sex-specific reservoir of TLR7 ligands in SLE JCI insight 2023-09-21 [PMID: 37733447] (Human)
• SY Bando, FB Bertonha, SE Vieira, DBL de Oliveir, VN Chalup, EL Durigon, P Palmeira, ACP Curi, CS Faria, L Antonangel, GDP Lauterbach, FA Regalio, RM Cesar, CA Moreira-Fi Blood leukocyte transcriptional modules and differentially expressed genes associated with disease severity and age in COVID-19 patients Scientific Reports, 2023-01-17;13(1):898. 2023-01-17 [PMID: 36650374] (Human)
• J Hong, JH Lee, Z Zhang, Y Wu, M Yang, Y Liao, R de la Rosa, J Scheirer, D Pechacek, N Zhang, Z Xu, T Curiel, X Tan, TH Huang, K Xu PRC2-mediated epigenetic suppression of type I IFN-STAT2 signaling impairs antitumor immunity in luminal breast cancer Cancer Research, 2022-12-16;0(0):. 2022-12-16 [PMID: 36222718] (Human)
• C Wilkinson, J Kyle, M Irimpen, S Stuart, S Mohandass, A Sheperd, KJ Smith, MJ Mullin Improved yield of recombinant human IFN-alpha2b from mammalian cells using heterologous signal peptide approach Protein Expression and Purification, 2022-06-02;198(0):106125. 2022-06-02 [PMID: 35659600] (Human)