HPS3 Antibody - BSA Free

Immunohistochemistry: HPS3 Antibody - BSA Free [NBP3-46085] - Immunohistochemistry of paraffin-embedded human colon cancer using (HPS3 antibody) at dilution of 1:100

Western Blot: HPS3 Antibody - BSA Free [NBP3-46085] - HeLa cells were subjected to SDS PAGE followed by western blot with (HPS3 antibody) at dilution of 1:300

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

HPS3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit HPS3 Antibody - BSA Free (NBP3-46085) is a polyclonal antibody validated for use in IHC, WB, ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Hermansky-Pudlak syndrome 3. (Uniprot# Q969F9)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HPS3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence 1:20-1:200
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 113 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for HPS3 Antibody - BSA Free

• DKFZp686F0413
• FLJ22704
• Hermansky-Pudlak syndrome 3 protein
• Hermansky-Pudlak syndrome 3
• SUTAL

Background

HPS3 is involved in early stages of melanosome biogenesis and maturation. Defects in HPS3 are the cause of the cocoa (coa) mutant, and of Hermansky-Pudlak syndrome type 3 (HPS3). HPS3 is an autosomal recessive disorder, characterized by oculocutaneous albinism, bleeding due to platelet storage pool deficiency, and lysosomal storage defects. This syndrome results from defects of diverse cytoplasmic organelles including melanosomes, platelet dense granules and lysosomes. Ceroid storage in the lungs is associated with pulmonary fibrosis, a common cause of premature death in individuals with HPS.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HPS3