HPS6 Antibody

Western Blot: HPS6 Antibody [NB300-931] - Staining of Human Lung lysate (RIPA buffer, 30 ug total protein per lane). Antibody at 1 ug/mL. Detected by chemiluminescence.

Immunohistochemistry-Paraffin: HPS6 Antibody [NB300-931] - Staining of paraffin embedded Human Cortex. Antibody at 5 ug/mL. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

• Reactivity: Hu, Mu, Rt, Po, Bv
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

HPS6 Antibody Summary

• Description: Novus Biologicals Goat HPS6 Antibody (NB300-931) is a polyclonal antibody validated for use in IHC, WB and ELISA. Anti-HPS6 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence LRTELRDYRGLEC corresponding to internal region according to NP_079023.
• Predicted Species: Mouse (100%), Rat (100%), Porcine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: HPS6
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 5 ug/mL
  • Peptide ELISA Detection limit 1:32000
  • Western Blot 1 - 3 ug/mL
• Application Notes: WB: Approx. 90-100 kDa band observed in human lung lysates (calculated MW of 83.0 kDa band according to NP_079023).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for HPS6 Antibody

• FLJ22501
• Hermansky-Pudlak syndrome 6 protein
• Hermansky-Pudlak syndrome 6
• Hermansky-Pudlak syndrome-6 protein (HPS6)
• MGC20522
• RP11-302K17.1
• Ru
• Ruby-eye protein homolog

Background

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for HPS6 Antibody (NB300-931)(1)

Publication using NB300-931

• Gautam R, Chintala S, Li W et al. The Hermansky-Pudlak syndrome 3 (cocoa) protein is a component of the biogenesis of lysosome-related organelles complex-2 (BLOC-2). J Biol Chem 2004-03-26 [PMID: 14718540]

Bioinformatics

• Gene Symbol: HPS6
• Entrez:
  • 79803(Human)
  • 20170(Mouse)
  • 309446(Rat)
• Uniprot:
  • NP_079023.(Human)