HOXD10 Antibody (OTI1D11) [mFluor Violet 450 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI1D11
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

HOXD10 Antibody (OTI1D11) [mFluor Violet 450 SE] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 80-340 of human HOXD10 (NP_002139) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: HOXD10
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HOXD10 Antibody (OTI1D11) [mFluor Violet 450 SE]

• homeo box 4D
• homeo box D10
• homeobox D10
• Homeobox protein Hox-4D
• Homeobox protein Hox-4E
• homeobox protein Hox-D10
• HOX4
• Hox-4.4
• HOX4D
• HOX4DHOX4
• HOX4E
• HOXD10

Background

HOXD10 is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as rocker-bottom foot deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HOXD10