HES-1 Antibody

Immunohistochemistry-Paraffin: HES-1 Antibody [NBP2-23657] - Analysis of HES-1 in formalin-fixed paraffin-embedded human brain tissue using an isotype control (top left) and this antibody (bottom left, right) at 1:2000.

Product Discontinued

HES-1 Antibody Summary

• Immunogen: A portion of amino acids 230-280 of human HES1 was used as the immunogen.
• Predicted Species: Porcine (100%), Chimpanzee (100%), Rhesus Macaque (100%), Opossum (94%), Canine (100%), Equine (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: HES1
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1: 1000-1:2000
  • Western Blot 1:500

Reactivity Notes

The amino acid sequence used as immunogen is 83% homologous in Xenopus and Chicken.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: 0.1 ml crude whole Rabbit sera with 50% Glycerol
• Preservative: 0.025% Sodium Azide
• Purity: Unpurified

Alternate Names for HES-1 Antibody

• BHLHB39
• bHLHb39hairy homolog (Drosophila)
• Class B basic helix-loop-helix protein 39
• FLJ20408
• Hairy and enhancer of split 1
• hairy and enhancer of split 1, (Drosophila)
• Hairy homolog
• Hairy-like protein
• HES1
• HES-1
• hHL
• HL
• HRY
• HRYHHL
• transcription factor HES-1

Background

Hes1 belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HES1
• Uniprot:
  • Q14469()