HDC2/PHC2 Antibody

Product Discontinued

HDC2/PHC2 Antibody Summary

• Immunogen: Polyclonal antibody raised in rabbit against mouse PHC2 (polyhomeotic homolog 2) using two KLH-conjugated synthetic peptides containing a sequence from the central region of the protein.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PHC2
• Purity: Unpurified

Applications/Dilutions

• Dilutions:
  • ELISA
• Application Notes: ELISA: 1:500.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Whole antisera with PBS
• Preservative: 0.05% Sodium Azide
• Purity: Unpurified

Alternate Names for HDC2/PHC2 Antibody

• early development regulator 2 (homolog of polyhomeotic 2)
• Early development regulatory protein 2
• EDR2
• HPH2
• MGC163502
• PH2
• polyhomeotic 2
• polyhomeotic homolog 2 (Drosophila)
• polyhomeotic-like 2 (Drosophila)
• polyhomeotic-like 2
• polyhomeotic-like protein 2

Background

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PHC2
• Uniprot:
  • Q8IXK0(Human)