HDC2/PHC2 Products

Description

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Uniprot	NP_004418.2 Human
Product By Gene ID	1912
Alternate Names	early development regulator 2 (homolog of polyhomeotic 2) Early development regulatory protein 2 EDR2 HPH2 MGC163502 PH2 polyhomeotic 2 polyhomeotic homolog 2 (Drosophila) polyhomeotic-like 2 (Drosophila) polyhomeotic-like 2 polyhomeotic-like protein 2

Research Areas for HDC2/PHC2

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Chromatin Modifiers