HCN4 Antibody (S114/10) [mFluor Violet 500 SE]

HCN4 Antibody (S114/10) [mFluor Violet 500 SE] - Vial of mFluor Violet 500 conjugated antibody. mFluor Violet 500 is optimally excited at 410 nm by the Violet laser (405 nm) and has an emission maximum of 501 nm.

• Reactivity: Hu, Mu, Rt, Rb
• Applications: Flow, ICC/IF, IHC
• Clone: S114/10
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 500 SE

HCN4 Antibody (S114/10) [mFluor Violet 500 SE] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Fusion protein amino acids 1019-1198 (c-terminus) of rat HCN4
• Localization: Membrane
• Specificity: Detects approx 130 kDa. No cross-reactivity against other HCNs.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: HCN4
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NBP2-12910. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Alternate Names for HCN4 Antibody (S114/10) [mFluor Violet 500 SE]

• HCN4
• hyperpolarization activated cyclic nucleotide-gated cation channel 4
• hyperpolarization activated cyclic nucleotide-gated potassium channel 4
• potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4
• SSS2

Background

HCN3 is a member of the family of hyperpolarization-activated and cyclic-nucleotide-gated (HCN) channels. HCN currents have been linked to pacemaker activity in the heart and brain, resting potential control, as well as neuronal plasticity. HCN3 has been detected in the brain, but with less expression than other HCN channels.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HCN4